Director, Global Health Economics

Job Description Summary

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending lifes moments for children and adults living with a rare disease.

At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.

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The Director of Global Health Economics & Outcomes Research Associate will participate in developing and implementing HEOR strategies that enhance the value proposition and supporting evidence of Sepiapterin, aiding its launch and post-launch phases. Additionally, the Director of HEOR is responsible for educating external customers about the clinical, economic, and humanistic impacts of PTC medicines and products to support formulary decision-making and improve population health. The Director of Global HEOR also ensures compliance with relevant regulatory requirements and company Standard Operating Procedures (SOPs).

• Leads the execution of complex HEOR evidence generation strategies, including cost-effectiveness analysis, budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses, systematic reviews, patient-reported outcomes measure development and validation, and other research necessary to support asset value.
• Collaborate with the In-House HEOR Team and Market Access Team to implement HEOR scientific engagement strategies for external customers, such as Payers, PBMs, GPOs, and Clinical Pathway companies, within a specific territory or customer base. Coordinate with other PTC colleagues as needed to ensure compliance and achieve HEOR goals.
• Serve as a conduit and resource for delivering scientific (clinical and healthcare economic information (HCEI)) to formulary decision-makers in accordance with PTC guidance.
• Proactively communicate clinical and economic information related to PTC disease or PTC product to support formulary decisions and enhance patient care outcomes.
• Respond to unsolicited customer requests for clinical and economic information related to PTC disease area or products to support formulary decisions and enhance patient outcomes.
• Capture and communicate customer insights with internal PTC's colleagues as appropriate, including identifying potential opportunities for research partnerships.
• Utilizes best practices to deliver essential input for designing PTC observational research studies.
• Collaborates with the medical communications teams on publication strategy and ensures that the dissemination of HEOR evidence is timely and maximizes impact.
• Collaborates internally with Medical, Clinical, Market Access, Regulatory, and Biostats to develop and implement HEOR strategies, supporting PTC product therapeutic value.
• Partners and works closely with Market Access to support the production of GVD and the Value Narrative.
• Perform other tasks and assignments as needed and specified by management.

• Advanced degree (PhD, PharmD, MS) in health economics, public health, or a related scientific discipline, along with a minimum of 7 years of cumulative experience in health economics and outcomes research, within a pharmaceutical, biotechnology, or related environment.
• Strong track record of publication in peer-reviewed journals
• Strong technical expertise in HEOR and can formulate and lead innovative research projects, ensuring conduct is scientifically rigorous and aligns with best HEOR practices.
• Strong verbal and written communication skills, including presentation abilities to explain complex concepts and persuade others; comfortable adapting presentation style to various audiences.
• Ability to apply knowledge of global health technology appraisal requirements and clinical development to identify evidence gaps and formulate evidence generation strategies
• Demonstrate a breadth of diverse leadership experiences and capabilities, including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues in a matrix environment to achieve meaningful outcomes and create business impact.
• Must possess a deep understanding of the current and future healthcare environment and a demonstrated ability to understand, interpret, and make recommendations concerning the evolving US healthcare marketplace.
• Strong analytic skills, including creativity and effectiveness in proactively identifying and addressing challenges.
• Strong comprehension and communication skills, including the ability to communicate large amounts of scientific information in a manner that is clear, concise, and memorable.
• Well-organized with the ability to be flexible, prioritize multiple demands, and employ strong situational leadership skills.
• Understanding of the legal and regulatory environment of the pharmaceutical industry, with a spotless history of compliance and ethical workplace conduct
• Ability to work independently and collaboratively, as required, in a fast-paced, matrixed team environment consisting of internal and external team members.
• Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
• Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.
• Travel requirements: 30% - International and domestic

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

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