Clinical Trial Manager

Clinical Trial Manager (Study Startup)

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.

As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

We are looking for an experienced Clinical Trial Manager, Study Start-Up to lead and coordinate study start-up activities and drive clinical trials toward timely site activation.

In this role, you will oversee key start-up deliverables, including regulatory and ethics submissions, documentation, start-up payments and associated fees , and cross-functional coordination to ensure studies are ready to begin on time.

What You Will Do:

• Lead and coordinate end-to-end study start-up activities , from study handover through site activation.

• Develop and manage study start-up plans, timelines, milestones, and key deliverables.

• Coordinate country and site feasibility, site selection, and activation activities .

• Drive preparation, collection, review, and tracking of essential start-up documentation.

• Coordinate regulatory and ethics submissions, approvals, and start-up requirements across countries and sites.

• Manage and track study start-up payments and fees , including regulatory, ethics committee/IRB, and other applicable start-up costs.

• Coordinate payment requests, supporting documentation, approvals, and follow-up to help ensure start-up payments are processed within required timelines .

• Partner with Regulatory, Finance, Clinical Operations, Contracts, and other stakeholders to resolve payment-related issues that could impact study initiation or site activation.

• Monitor overall start-up progress and proactively identify and resolve risks, bottlenecks, and potential delays.

• Provide stakeholders with clear updates on start-up timelines, submissions, payments, approvals, risks, and site activation status .

• Ensure activities are conducted in accordance with applicable SOPs, ICH-GCP , and regulatory requirements.

• Contribute to process improvements that enhance the efficiency and quality of study start-up activities.

Your Profile:

• Bachelor’s degree in Life Sciences, Healthcare, or a related discipline.

• Strong experience in clinical research and study start-up , ideally within a CRO, biotech, or pharmaceutical environment.

• Experience managing start-up activities across multiple sites and/or countries.

• Good understanding of regulatory and ethics submissions, essential documents, start-up payments/fees, and site activation processes .

• Experience coordinating regulatory, ethics committee/IRB, and other study start-up payment requirements .

• Strong project management skills with the ability to manage multiple timelines, dependencies, and stakeholders.

• Good knowledge of ICH-GCP and applicable clinical research regulations.

• Strong communication, organizational, and problem-solving skills with the ability to proactively drive activities to completion.

• Must be amenable to work in a hybrid setup (2-3x a week onsite in Makati)

What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements

• A range of health insurance offerings to suit you and your family’s needs.

• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.

• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.

• Life assurance

• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site ( to read more about the benefits ICON offers.

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